Why Get a Priapus* Shot (P-shot)?

*Priapus was a minor Greek fertility god, protector of livestock, fruit plants, gardens and male genitalia. Priapus was depicted as having an oversized, permanent erection.

I am often asked why would any man voluntarily get injected in his penis. What is this P-shot anyway? What are the benefits? What are the risks?

What is the P-shot?

The P-shot is the injection of platelet-rich plasma (PRP) into the erectile tissue of the penis. PRP is a concentrate of your own blood prepared by removing the red blood cells and preserving platelets which are small fragments of cells that involved in forming blood clots. When activated, platelets release a variety of growth factors that induce new tissue formation including, but not limited to, blood vessel formation (neovascularization).

Introduction of PRP into the erectile tissue therefore brings about both structural changes and new blood vessel formation.

How is the P-shot performed?

Under sterile conditions, we collect a single tube of blood and spin it in a centrifuge to prepare the PRP. 

Your penis is numbed with a topical anesthetic cream containing lidocaine (similar to a dental anesthetic) for 45 minutes.  The cream is then removed and the top side of the penis is treated with an antiseptic wash to create a sterile field.

The PRP is then injected in four places along the shaft  and once near the tip of the penis with a very fine 1/2” needle. There is some mild discomfort with the injection but not pain. The injections take less than five minutes. A penis pump is then applied to distribute the PRP throughout the erectile bodies. Minor bruising is sometimes seen at the injection sites.

(Note: If you have Peyronie’s Disease, then some PRP is also injected into the plaque directly).

Why get a P-shot?

There are three primary indications for getting P-shots:

Peyronie’s Disease : Research indicates that combining P-shots with either GAINSWave or vacuum therapy (the pump) improves Peyronies symptoms

Severe Erectile Dysfunction : We need to “pull out all the stops” for you guys and there research to indicate that P-shots can assist to in nerve regeneration.

Size : Anecdotal and preliminary research indicates that size gains can be obtained with P-shots and vacuum therapy.

However, everyone with erectile dysfunction will benefit from a P-shot.


Some Variations on the P-shot Theme:

Lichen sclerosis (aka BXO) : this is an autoimmune disorder where the skin near the tip of the penis become thin and ulcerated. Injection of PRP directly into these areas has been shown to help resolve these lesions. 

Bicycle seat nerve damage: An important set of nerves for erectile function runs just under the skin between the scrotum and the anus (exactly where a man sits on a standard bicycle seat). These nerves can and do become damaged from cycling (there is even a CDC warning about this issue). PRP injections into this area can help regenerate the nerves and restore function.  

What are the risks of getting a P-shot?

There is always a risk of bleeding and infection with any injection, however these are very unlikely and treatable. The PRP itself is safe and we use FDA-approved tubes for the collection and preparation of the PRP. 

When should I expect results? Will I need more than one P-shot?

Results are not immediate (though your penis will be slightly swollen for a couple of days while the PRP resorbs). New growth takes time (months). After six months, we reassess the effect of the shot plus the supplemental vacuum therapy. At that point, a second shot may be indicated. (Note that these guidelines apply to shots by themselves and not part of a GAINSWave package).